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Heterogeneous Nuclear Ribonucleoprotein H3 (HNRNPH3) Antibody
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Catalogue No: abx029267
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.
Research Articles on Heterogeneous Nuclear Ribonucleoprotein H3 (HNRNPH3)
| Target | Heterogeneous Nuclear Ribonucleoprotein H3 (HNRNPH3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 90-117 amino acids from the Central region of human HNRNPH3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P31942 (UniProt, ExPASy) |
| UniProt Entry Name | HNRH3_HUMAN |
| Gene Symbol | HNRNPH3 |
| GeneID | 3189 |
| OMIM | 602324 |
| HGNC | 5043 |
| KEGG | hsa:3189 |
| Ensembl | ENSG00000096746 |
| String | 9606.ENSP00000265866 |
| Molecular Weight | Calculated MW: 36.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |