Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) Antibody

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.

Target	Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human HS2ST1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q7LGA3 (UniProt, ExPASy)
UniProt Secondary AC	D3DT22, O75036, Q32NB5, Q8TAC5, Q9H441, Q9NUJ9
UniProt Entry Name	HS2ST_HUMAN
KEGG	hsa:9653
String	9606.ENSP00000359581
Molecular Weight	Calculated MW: 41.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1)

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