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Heat Shock Protein 90 kDa Alpha A1 (HSP90AA1) Antibody
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Catalogue No: abx010953
Price:
US$406.00
(Size: 100 µg)
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Heat Shock Protein 90 kDa Alpha A1 (HSP90AA1) Antibody is a Rabbit Polyclonal antibody for the detection of HSP90AA1. HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.
Research Articles on Heat Shock Protein 90 kDa Alpha A1 (HSP90AA1)
| Target | Heat Shock Protein 90 kDa Alpha A1 (HSP90AA1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | heat shock protein 90kDa alpha(cytosolic), class A member 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P07900 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K500, B3KPJ9, Q2PP14, Q5CAQ6, Q5CAQ7, Q9BVQ5 |
| UniProt Entry Name | HS90A_HUMAN |
| Gene Symbol | HSP90AA1 |
| GeneID | 3320 |
| OMIM | 140571 |
| HGNC | 5253 |
| KEGG | hsa:3320 |
| Ensembl | ENSG00000080824 |
| String | 9606.ENSP00000335153 |
| Molecular Weight | Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |