Heat Shock 70 kDa Protein 6 (HSPA6) Antibody

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Target	Heat Shock 70 kDa Protein 6 (HSPA6)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 544-571 amino acids from the C-terminal region of human HSPA6.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17066 (UniProt, ExPASy)
UniProt Secondary AC	Q1HBA8, Q8IYK7, Q9BT95
UniProt Entry Name	HSP76_HUMAN
Gene Symbol	HSPA6
KEGG	hsa:3310
String	9606.ENSP00000310219
Molecular Weight	Calculated MW: 71 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Heat Shock 70 kDa Protein 6 (HSPA6)

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