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5-Hydroxytryptamine Receptor 1B (HTR1B) Antibody
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Catalogue No: abx028152
Price:
US$290.00
(Size: 80 µl)
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The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.
Research Articles on 5-Hydroxytryptamine Receptor 1B (HTR1B)
| Target | 5-Hydroxytryptamine Receptor 1B (HTR1B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 225-253 amino acids from the Central region of human HTR1B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28222 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VAY7 |
| UniProt Entry Name | 5HT1B_HUMAN |
| Gene Symbol | HTR1B |
| KEGG | hsa:3351 |
| String | 9606.ENSP00000358963 |
| Molecular Weight | Calculated MW: 43.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig and Horse HTR1B. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |