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5-Hydroxytryptamine Receptor 2B (HTR2B) Antibody
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Catalogue No: abx004337
Price:
US$203.00
(Size: 20 µl)
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HTR2B Antibody is a Rabbit Polyclonal antibody against HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.
Research Articles on 5-Hydroxytryptamine Receptor 2B (HTR2B)
| Target | 5-Hydroxytryptamine Receptor 2B (HTR2B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P41595 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9D5, Q53TI1, Q62221, Q6P523 |
| UniProt Entry Name | 5HT2B_HUMAN |
| Gene Symbol | HTR2B |
| GeneID | 3357 |
| NCBI Accession | NP_000858.3 |
| KEGG | hsa:3357 |
| String | 9606.ENSP00000258400 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 47 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 2.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |