Human Anti-ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13 / vWFCP Antibody (Anti-ADAMTS13) ELISA Kit

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Catalogue No: abx585413
Price: US$862.75
(Size: 96 tests)

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Human Anti-ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13 / vWFCP Antibody (Anti-ADAMTS13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human vWFCP Antibody (Anti-ADAMTS13) concentrations in serum, plasma and other biological fluids.

Introduction Anti-ADAMTS13 (also known as ADAMTS13 Inhibitor) are autoantibodies capable of targeting the ADAMTS13 protein to inhibit it and target it for degradation. Its target is responsible for cleaving von Willebrand Factor (vWF) multimers, inactivating them. These autoantibodies are often found in patients with Thrombotic Thrombocytopenic Purpura (TTP), where the depletion of ADAMTS13 leads to the creation of small platelet clots dispersed around the vasculature, causing a low platelet count and damaging passing red blood cells. TTP is treated by plasmapheresis, which removes the patient's plasma and replaces it with donor plasma. This helps restore appropriate ADAMTS13 concentrations and remove autoantibodies.
Target Anti-ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13 / vWFCP Antibody (Anti-ADAMTS13)
Reactivity Human
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
Test Range 3.12 ng/ml - 200 ng/ml
Sensitivity < 1.17 ng/ml
Standard Form Lyophilized
Detection Method Colorimetric
Assay Type Indirect
Assay Data Quantitative
Sample Type Serum, plasma and other biological fluids.
Target Type Antibody
Availability Shipped within 5-7 working days.
Note This product is for research use only.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Standard 200 ng/ml
Research Articles on Anti-ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13 / vWFCP Antibody (Anti-ADAMTS13)


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