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Introduction | Onchocerca volvulus is a nematode parasite that causes the tropical disease onchocerciasis, otherwise known as river blindness. The disease is transmitted by the Simuliidae family of black flies, which carry the parasite larvae. Humans are the only other known host for the parasites. When an infected black fly takes a blood meal, the parasites enter the subcutaneous skin layers and reproduce, causing limited local skin inflammation. The parasites also carry Wolbachia bacteria, which are released when the parasite is killed, causing more severe inflammation. Blindness occurs as a result of the parasites migrating to the cornea and causing inflammation there. A vaccine against the disease is under production, and the disease is primarily treated using ivermectin, however doxycycline and moxidectin are also sometimes used. |
Target | Anti-Onchocerca volvulus IgG |
Reactivity | Human |
Tested Applications | ELISA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | The validity for this kit is 6 months. |
Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Assay Type | Indirect |
Assay Data | Qualitative |
Sample Type | Serum, plasma, cell culture supernatants and tissue homogenates. |
Availability | Shipped within 5-10 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Plate coated with | Antigen |