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Human Aquaporin 2 (AQP2) CLIA Kit
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Catalogue No: abx195181
Price:
US$717.75
(Size: 96 tests)
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Human Aquaporin 2 (AQP-2) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Aquaporin 2 (AQP-2).
Research Articles on Aquaporin 2 (AQP2)
| Introduction | Aquaporin 2 (AQP2) is a member of a family of proteins that allow water to enter and exit the cell more easily than they would do so if relying on osmosis alone through hydrophobic lipid bilayers. AQP2 is found on the collecting ducts of the kidneys, where it reabsorbs water from urine. Vasopressin increases the levels of AQP2 by stimulating the fusion of AQP2 trafficking vesicles to the cell membrane, and by increasing expression of the AQP2 gene. Some cases of diabetes insipidus can be caused by low levels of AQP2, either through genetically-induced deficiency, or from the downregulation resulting from the intake of lithium salts. |
| Target | Aquaporin 2 (AQP2) |
| Reactivity | Human |
| Tested Applications | CLIA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is 6 months. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| UniProt Primary AC | P41181 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UD68 |
| UniProt Entry Name | AQP2_HUMAN |
| Gene Symbol | AQP2 |
| GeneID | 359 |
| OMIM | 107777 |
| HGNC | 634 |
| KEGG | hsa:359 |
| Ensembl | ENSG00000167580 |
| String | 9606.ENSP00000199280 |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Standard Form | Lyophilized |
| Detection Method | Chemiluminescent |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Plate coated with | Antibody |