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Introduction | Factor IX (F9, also known as Christmas factor) is a blood protein that forms an integral part of the coagulation cascade. It is cleaved into active factor IX (F9a) by factors XIa and VIIa, after which it can use factor VIIIa as a cofactor to activate factor X. Low levels of factor IX occur in the X-linked genetic disorder Haemophilia B, also known as “the royal disease” due to its high rate of occurrence in Queen Victoria’s descendants, or Christmas disease as it was first described in a child named Stephen Christmas. This disorder causes a reduction in clotting capability, increasing the risks from and frequency of bleeds. |
Target | Coagulation Factor IX (F9) |
Reactivity | Human |
Tested Applications | CLIA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Test Range | 13.7 pg/ml - 10000 pg/ml |
Sensitivity | < 5.5 pg/ml |
Standard Form | Lyophilized |
Detection Method | Chemiluminescent |
Assay Type | Sandwich |
Assay Data | Quantitative |
Sample Type | Plasma. |
Availability | Shipped within 5-12 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Standard | 10000 pg/ml |