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Human Free Prostate-Specific Antigen / f-PSA (Free-KLK3) Protein
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Catalogue No: abx060128
Price:
US$522.00
(Size: 100 µg)
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Human Free Prostate-Specific Antigen (PSA) / Kallikrein 3 (KLK3) Protein is a native protein isolated from Human seminal fluid. Prostate-specific antigen (PSA), also known as gamma-seminoprotein or Kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in Humans by the KLK3 gene. PSA is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer cells and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific. PSA is a major protein in semen, where its function is to cleave semenogelins in the seminal coagulum. PSA is secreted into prostatic ducts as an inactive 244-amino acid proenzyme (proPSA) that is activated by cleavage of seven N-terminal amino acids.
Research Articles on Free Prostate-Specific Antigen / f-PSA (Free-KLK3)
| Target | Free Prostate-Specific Antigen / f-PSA (Free-KLK3) |
| Origin | Human |
| Expression | Native |
| Tested Applications | ELISA |
| Host | Human |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Liquid |
| Purity | > 90% (SDS-PAGE) |
| Purification | Purified from Human seminal fluid. |
| Storage | Aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P07288 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4 |
| UniProt Entry Name | KLK3_HUMAN |
| Gene Symbol | KLK3 |
| GeneID | 354 |
| OMIM | 176820 |
| HGNC | 6364 |
| KEGG | hsa:354 |
| Ensembl | ENSG00000142515 |
| String | 9606.ENSP00000314151 |
| Buffer | 0.01 M PBS (pH 7.4 ± 0.2). Does not contain preservatives. |
| Activity | Not tested |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |