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Human Macrophage Receptor MARCO (MARCO) ELISA Kit
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Catalogue No: abx385113
Price:
US$797.50
(Size: 96 tests)
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Human Macrophage Receptor MARCO (MARCO) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MARCO concentrations in tissue homogenates, cell lysates and other biological fluids.
Research Articles on Macrophage Receptor MARCO (MARCO)
| Introduction | Macrophage receptor MARCO, also known as macrophage receptor with collagenous structure (MARCO), is a class A scavenger receptor that is found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors (PRRs) and are most commonly found on immune cells. Their defining feature is that they bind to polyanions and low-density lipoproteins (LDLs). MARCO is able to bind and phagocytose these ligands and pathogen-associated molecular patterns (PAMPs), leading to the clearance of pathogens as well as causing downstream effects in the cell that lead to inflammation. MARCO expression on macrophages is also associated with diseases since Alzheimer's disease is associated with decreased response within the cell when a ligand binds to MARCO. |
| Target | Macrophage Receptor MARCO (MARCO) |
| Reactivity | Human |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is 6 months. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| UniProt Primary AC | Q9UEW3 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DW79, Q9Y5S3 |
| UniProt Entry Name | MARCO_HUMAN |
| Gene Symbol | MARCO |
| GeneID | 8685 |
| OMIM | 604870 |
| HGNC | 6895 |
| KEGG | hsa:8685 |
| Ensembl | ENSG00000019169 |
| String | 9606.ENSP00000318916 |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.13 ng/ml |
| Standard Form | Lyophilized |
| Detection Method | Colorimetric |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 20 ng/ml |