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Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit
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Catalogue No: abx384944
Price:
US$797.50
(Size: 96 tests)
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This product is currently under production. The lead time for this product may be several months. Please contact us at [email protected] for the lead time before purchasing this product. Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MAS Related GPR Member X2 (MRGPRX2) concentrations in Tissue homogenates, cell lysates and other biological fluids.
Research Articles on MAS Related GPR Member X2 (MRGPRX2)
| Introduction | Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene. MRGPRX2 recognises and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. Activation in response to these compounds results in mast cell degranulation with subsequent pseudo-allergic reactions, characterised by histamine release, inflammation and airway contraction. |
| Target | MAS Related GPR Member X2 (MRGPRX2) |
| Reactivity | Human |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| UniProt Primary AC | Q96LB1 (UniProt, ExPASy) |
| UniProt Entry Name | MRGX2_HUMAN |
| Gene Symbol | MRGPRX2 |
| GeneID | 117194 |
| OMIM | 607228 |
| HGNC | 17983 |
| KEGG | hsa:117194 |
| Ensembl | ENSG00000183695 |
| String | 9606.ENSP00000333800 |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Standard Form | Lyophilized |
| Detection Method | Colorimetric |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Please enquire. |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 100 ng/ml |
| Intra Assay | CV ≤ 5.3% |
| Inter Assay | CV ≤ 7.9% |