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Human Neurofilament, Light Polypeptide (NEFL) ELISA Kit
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Catalogue No: abx494482
US$942.50
US$895.38
(Size: 96 tests)
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Human Neurofilament, Light Polypeptide (NEFL) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cerebrospinal fluid, cell culture supernates and other biological fluids.
Research Articles on Neurofilament, Light Polypeptide (NEFL)
| Introduction | Neurofilament Light Polypeptide (NEFL) is one of five proteins that commonly form filaments in neuronal cells, with the other four being Neurofilament Medium and Heavy Polypeptide, as well as either peripherin or internexin. Together, these form neurofilaments, which form part of the neuronal cytoskeleton. NEFL and NEFM are found in close proximity to each other on human chromosome 8 and share some homology, suggesting that one could be the product of an ancestral gene duplication of the other. NEFL found in plasma or cerebrospinal fluid is used as a biomarker of nerve damage in multiple sclerosis and Alzheimer’s. Mutations in NEFL are associated with Charcot-Marie-Tooth disease. |
| Target | Neurofilament, Light Polypeptide (NEFL) |
| Reactivity | Human |
| Tested Applications | CLIA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| Test Range | 1.37 pg/ml - 1000 pg/ml |
| Sensitivity | < 0.63 pg/ml |
| Standard Form | Lyophilized |
| Detection Method | Chemiluminescent |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cerebrospinal fluid, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 1000 pg/ml |
