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Human Neuromedin U (NMU) CLIA Kit
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Catalogue No: abx490352
Price:
US$942.50
(Size: 96 tests)
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Human Neuromedin U (NMU) Chemiluminescent Immunoassay (CLIA) Kit is a Competitive Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.
Research Articles on Neuromedin U (NMU)
| Introduction | Neuromedin U (NMU) is a neuropeptide found in the brain of humans and other mammals, which has a number of diverse functions including contraction of smooth muscle, regulation of blood pressure, pain perception, appetite, bone growth, and hormone release. The activation of NMU receptors leads to intracellular signal transduction via calcium mobilization, phosphoinositide (or PI) signaling, and the inhibition of cAMP production. Neuromedin U is mediated by two receptors, peripheral NMUR1 and central nervous system NMUR2. Both receptors are examples of Class A G-protein coupled receptors (or GPCRs) with a distinct distributional pattern. NMUR1 is expressed predominantly in the peripheral nervous system, with highest levels in the gastrointestinal tract, whereas NMUR2 is mostly found in the central nervous system, with greatest expression in the hypothalamus, medulla, and spinal cord. |
| Target | Neuromedin U (NMU) |
| Reactivity | Human |
| Tested Applications | CLIA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| Test Range | 39 pg/ml - 10000 pg/ml |
| Sensitivity | < 18.4 pg/ml |
| Standard Form | Lyophilized |
| Detection Method | Chemiluminescent |
| Assay Type | Competitive |
| Assay Data | Quantitative |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 10000 pg/ml |
