+44 (0) 1223 755950
+1 832 327 7413
Human Phenylalanine Hydroxylase (PAH) CLIA Kit
REQUEST MORE INFO
Catalogue No: abx493878
Price:
US$942.50
(Size: 96 tests)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Add to Shopping Cart
Buy It Now
GET A QUOTE
Human Phenylalanine Hydroxylase (PAH) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Research Articles on Phenylalanine Hydroxylase (PAH)
| Introduction | Phenylalanine hydroxylase (PAH) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH4) and a non-heme iron for catalysis. It is is the rate-limiting step in the reaction, where molecular oxygen is heterolytically cleaved with sequential incorporation of one oxygen atom into BH4 and phenylalanine substrate. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. |
| Target | Phenylalanine Hydroxylase (PAH) |
| Reactivity | Human |
| Tested Applications | CLIA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| Test Range | 0.137 ng/ml - 100 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Standard Form | Lyophilized |
| Detection Method | Chemiluminescent |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 100 ng/ml |
