Human Proteasome Subunit Beta Type 1 (PSMB1) ELISA Kit

Human Proteasome Subunit Beta Type 1 (PSMB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Beta Type 1 (PSMB1) concentrations in tissue homogenates, cell lysates and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.

Target	Proteasome Subunit Beta Type 1 (PSMB1)
Reactivity	Human
Tested Applications	ELISA
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Storage	Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity	The validity for this kit is 6 months.
Stability	The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
UniProt Primary AC	P20618 (UniProt, ExPASy)
UniProt Secondary AC	B5BU76, Q9BWA8
UniProt Entry Name	PSB1_HUMAN
Gene Symbol	PSMB1
GeneID	5689
OMIM	602017
HGNC	9537
KEGG	hsa:5689
Ensembl	ENSG00000008018
String	9606.ENSP00000262193
Test Range	0.78 ng/ml - 50 ng/ml
Sensitivity	< 0.35 ng/ml
Standard Form	Lyophilized
Detection Method	Colorimetric
Assay Type	Sandwich
Assay Data	Quantitative
Sample Type	Tissue homogenates, cell lysates and other biological fluids.
Availability	Shipped within 5-15 working days.
Note	This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Research Articles on Proteasome Subunit Beta Type 1 (PSMB1)

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