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Huntingtin (HTT) Antibody
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Catalogue No: abx239896
Price:
US$406.00
(Size: 100 µg)
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Huntingtin (HTT) Antibody is a Rabbit Polyclonal antibody for the detection of Huntingtin. HTT (huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.
Research Articles on Huntingtin (HTT)
| Target | Huntingtin (HTT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Huntingtin |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P42858 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UQB7 |
| UniProt Entry Name | HD_HUMAN |
| Gene Symbol | HTT |
| GeneID | 3064 |
| OMIM | 143100 |
| HGNC | 4851 |
| KEGG | hsa:3064 |
| Ensembl | ENSG00000197386 |
| String | 9606.ENSP00000347184 |
| Molecular Weight | Observed MW: 348 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |