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Hyaluronidase-3 (HYAL3) Antibody
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Catalogue No: abx005312
Price:
US$217.50
(Size: 20 µl)
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HYAL3 Antibody is a Rabbit Polyclonal antibody against HYAL3. This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
Research Articles on Hyaluronidase-3 (HYAL3)
| Target | Hyaluronidase-3 (HYAL3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 198-417 of human HYAL3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43820 (UniProt, ExPASy) |
| UniProt Secondary AC | O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9 |
| UniProt Entry Name | HYAL3_HUMAN |
| Gene Symbol | HYAL3 |
| GeneID | 8372 |
| NCBI Accession | NP_003540.2 |
| KEGG | hsa:8372 |
| String | 9606.ENSP00000337425 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 47 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |