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Integrin-Binding Sialoprotein (IBSP) Antibody
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Catalogue No: abx027806
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Research Articles on Integrin-Binding Sialoprotein (IBSP)
| Target | Integrin-Binding Sialoprotein (IBSP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human IBSP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P21815 (UniProt, ExPASy) |
| UniProt Entry Name | SIAL_HUMAN |
| Gene Symbol | IBSP |
| KEGG | hsa:3381 |
| String | 9606.ENSP00000226284 |
| Molecular Weight | Calculated MW: 35.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |