+44 (0) 1223 755950
+1 832 327 7413
DNA-Binding Protein Inhibitor ID-4 (ID4) Antibody
REQUEST MORE INFO
Catalogue No: abx034601
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
Research Articles on DNA-Binding Protein Inhibitor ID-4 (ID4)
| Target | DNA-Binding Protein Inhibitor ID-4 (ID4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ID4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P47928 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13005 |
| UniProt Entry Name | ID4_HUMAN |
| KEGG | hsa:3400 |
| String | 9606.ENSP00000367972 |
| Molecular Weight | Calculated MW: 16.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig ID4. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |