+44 (0) 1223 755950
+1 832 327 7413
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody
REQUEST MORE INFO
Catalogue No: abx033407
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
![Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody](https://www.abbexa.com/image/cache/data/products/10A/abx033407_IDH1_Antibody_IF_1-500x500.jpg "Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody")
![Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody](https://www.abbexa.com/image/cache/data/products/10A/abx033407_IDH1_Antibody_IHC_1-500x500.jpg)
![Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody](https://www.abbexa.com/image/cache/data/products/10A/abx033407_IDH1_Antibody_WB_1-500x500.jpg)
![Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody](https://www.abbexa.com/image/cache/catalog/Antibody_Box-500x500.png)
Click on the image to see the image legend
IDH1 belongs to two distinct subclasses. The protein is the NADP (+) dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Research Articles on Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1)
| Target | Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75874 (UniProt, ExPASy) |
| UniProt Secondary AC | Q567U4, Q6FHQ6, Q7Z3V0, Q93090, Q9NTJ9, Q9UKW8 |
| UniProt Entry Name | IDHC_HUMAN |
| NCBI Accession | NP_001269315.1 NP_001269316.1 NP_005887.2 |
| KEGG | hsa:3417 |
| String | 9606.ENSP00000390265 |
| Molecular Weight | Calculated MW: 46.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Cow and Sheep IDH1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |