Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody

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Catalogue No: abx033407
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
IDH1 belongs to two distinct subclasses. The protein is the NADP (+) dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.

Target Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1.
Isotype IgG
Form Liquid
Purification Purified Rabbit Polyclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75874 (UniProt, ExPASy)
UniProt Secondary AC Q567U4, Q6FHQ6, Q7Z3V0, Q93090, Q9NTJ9, Q9UKW8
UniProt Entry Name IDHC_HUMAN
NCBI Accession NP_001269315.1 NP_001269316.1 NP_005887.2
KEGG hsa:3417
String 9606.ENSP00000390265
Molecular Weight Calculated MW: 46.7 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat, Cow and Sheep IDH1.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1)


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