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Isocitrate Dehydrogenase [NAD] Subunit Gamma, Mitochondrial (IDH3G) Antibody
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Catalogue No: abx034520
Price:
US$326.25
(Size: 80 µl)
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+) dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD (+) dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD (+) dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.
Research Articles on Isocitrate Dehydrogenase [NAD] Subunit Gamma, Mitochondrial (IDH3G)
| Target | Isocitrate Dehydrogenase [NAD] Subunit Gamma, Mitochondrial (IDH3G) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human IDH3G. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51553 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PDD5, Q9BUU5 |
| UniProt Entry Name | IDH3G_HUMAN |
| KEGG | hsa:3421 |
| String | 9606.ENSP00000217901 |
| Molecular Weight | Calculated MW: 42.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Monkey IDH3G. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |