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Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody
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Catalogue No: abx001815
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US$217.50
(Size: 20 µl)
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IFIH1 Antibody is a Rabbit Polyclonal antibody against IFIH1. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Research Articles on Interferon Induced With Helicase C Domain 1 (IFIH1)
| Target | Interferon Induced With Helicase C Domain 1 (IFIH1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human IFIH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BYX4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2NKL6, Q6DC96, Q86X56, Q96MX8, Q9H3G6 |
| UniProt Entry Name | IFIH1_HUMAN |
| Gene Symbol | IFIH1 |
| GeneID | 64135 |
| NCBI Accession | NP_071451.2 |
| String | 9606.ENSP00000263642 |
| Molecular Weight | Calculated MW: 117 kDa Observed MW: 117 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 0.75 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |