Interferon Beta 1 (IFNB1) Antibody

IFNB1 Antibody is a Rabbit Polyclonal antibody against IFNB1. The genes encoding type I interferons (IFNs), which include 14 IFN-alpha genes, one IFN-beta gene, one IFN-omega (also known as IFN-alpha II1) gene, and a number of IFN-omega pseudogenes, are clustered on human chromosome 9. Interferons-alpha and beta are cytokines that are widely known to induce potent antiviral activity. IFN-alpha and beta exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-omega is antigenically different from human IFN-alpha, IFN-beta or IFN-gamma, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFNAR) interacts with IFN-alpha, IFN-beta and IFN-omega, and seems to be a multisubunit receptor.

Target	Interferon Beta 1 (IFNB1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-187 of human IFN-beta.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01574 (UniProt, ExPASy)
UniProt Secondary AC	Q5VWC9
UniProt Entry Name	IFNB_HUMAN
Gene Symbol	IFNB1
GeneID	3456
NCBI Accession	NP_002167.1
KEGG	hsa:3456
String	9606.ENSP00000369581
Molecular Weight	Calculated MW: 22 kDa Observed MW: 22 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	2.76 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon Beta 1 (IFNB1)

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