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IGF1R (pY1161) Antibody
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Catalogue No: abx000415
Price:
US$232.00
(Size: 20 µl)
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IGF1R (pY1161) Antibody is a Rabbit Polyclonal antibody against IGF1R (pY1161). This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Research Articles on IGF1R (pY1161)
| Target | IGF1R (pY1161) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around Y1161 of human IGF1R. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08069 (UniProt, ExPASy) |
| UniProt Secondary AC | B1B5Y2, Q14CV2, Q9UCC0 |
| UniProt Entry Name | IGF1R_HUMAN |
| Gene Symbol | IGF1R |
| GeneID | 3480 |
| NCBI Accession | NP_000866.1 |
| KEGG | hsa:3480 |
| String | 9606.ENSP00000268035 |
| Molecular Weight | Calculated MW: 155 kDa Observed MW: 95 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |