Zinc Finger Protein Aiolos (IKZF3) Antibody

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Target	Zinc Finger Protein Aiolos (IKZF3)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 76-103 amino acids from the Central region of human IKZF3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UKT9 (UniProt, ExPASy)
UniProt Entry Name	IKZF3_HUMAN
Gene Symbol	IKZF3
String	9606.ENSP00000344544
Molecular Weight	Calculated MW: 58 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow IKZF3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Zinc Finger Protein Aiolos (IKZF3)

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