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Zinc Finger Protein Aiolos (IKZF3) Antibody
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Catalogue No: abx005494
Price:
US$203.00
(Size: 20 µl)
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IKZF3 Antibody is a Rabbit Polyclonal antibody against IKZF3. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Research Articles on Zinc Finger Protein Aiolos (IKZF3)
| Target | Zinc Finger Protein Aiolos (IKZF3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 280-450 of human IKZF3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UKT9 (UniProt, ExPASy) |
| UniProt Entry Name | IKZF3_HUMAN |
| Gene Symbol | IKZF3 |
| GeneID | 22806 |
| NCBI Accession | NP_036613.2 |
| String | 9606.ENSP00000344544 |
| Molecular Weight | Calculated MW: 58 kDa Observed MW: 58 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |