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Interleukin 18 Binding Protein (IL18BP) Antibody
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Catalogue No: abx004938
Price:
US$217.50
(Size: 20 µl)
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IL18BP Antibody is a Rabbit Polyclonal antibody against IL18BP. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Articles on Interleukin 18 Binding Protein (IL18BP)
| Target | Interleukin 18 Binding Protein (IL18BP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95998 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KUZ0, B7WPK4, O95993, O96027, Q9NZA9, Q9UBR7 |
| UniProt Entry Name | I18BP_HUMAN |
| Gene Symbol | IL18BP |
| GeneID | 10068 |
| NCBI Accession | NP_001138529.1 |
| KEGG | hsa:10068 |
| String | 9606.ENSP00000384212 |
| Molecular Weight | Calculated MW: 21 kDa Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |