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Interleukin-1 Receptor Type 1 (IL1R) Antibody
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Catalogue No: abx032810
Price:
US$326.25
(Size: 80 µl)
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IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Research Articles on Interleukin-1 Receptor Type 1 (IL1R)
| Target | Interleukin-1 Receptor Type 1 (IL1R) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14778 (UniProt, ExPASy) |
| UniProt Secondary AC | Q587I7 |
| UniProt Entry Name | IL1R1_HUMAN |
| KEGG | hsa:3554 |
| String | 9606.ENSP00000386380 |
| Molecular Weight | Calculated MW: 65.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat IL1R1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |