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Interleukin 24 (IL24) Antibody
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Catalogue No: abx001544
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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IL24 Antibody is a Rabbit Polyclonal antibody against IL24. This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Research Articles on Interleukin 24 (IL24)
| Target | Interleukin 24 (IL24) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human IL24 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13007 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2YHE5, Q53XZ7, Q5YLN8, Q96DB0, Q96KG4 |
| UniProt Entry Name | IL24_HUMAN |
| Gene Symbol | IL24 |
| GeneID | 11009 |
| NCBI Accession | NP_001172085.1 |
| KEGG | hsa:11009 |
| String | 9606.ENSP00000375795 |
| Molecular Weight | Calculated MW: 7 kDa/17 kDa/23 kDa Observed MW: 26 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
