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Interleukin-27 Subunit Alpha (IL27) Antibody
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Catalogue No: abx027891
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Research Articles on Interleukin-27 Subunit Alpha (IL27)
| Target | Interleukin-27 Subunit Alpha (IL27) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 126-154 amino acids from the Central region of human IL27. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NEV9 (UniProt, ExPASy) |
| UniProt Secondary AC | A0N0L2, Q6P676 |
| UniProt Entry Name | IL27A_HUMAN |
| Gene Symbol | IL27 |
| KEGG | hsa:246778 |
| String | 9606.ENSP00000349365 |
| Molecular Weight | Calculated MW: 27.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |