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Interleukin 2 Receptor Beta (IL2RB) Antibody
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Catalogue No: abx004743
Price:
US$348.00
(Size: 60 µl)
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IL2RB Antibody is a Rabbit Polyclonal antibody against IL2RB. The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Research Articles on Interleukin 2 Receptor Beta (IL2RB)
| Target | Interleukin 2 Receptor Beta (IL2RB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human IL2RB |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14784 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R765 |
| UniProt Entry Name | IL2RB_HUMAN |
| Gene Symbol | IL2RB |
| GeneID | 3560 |
| NCBI Accession | NP_000869.1 |
| KEGG | hsa:3560 |
| String | 9606.ENSP00000216223 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |