Interleukin 2 Receptor Beta (IL2RB) Antibody

IL2RB Antibody is a Rabbit Polyclonal antibody against IL2RB. The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Target	Interleukin 2 Receptor Beta (IL2RB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 316-431 of human IL2RB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14784 (UniProt, ExPASy)
UniProt Secondary AC	B2R765
UniProt Entry Name	IL2RB_HUMAN
Gene Symbol	IL2RB
GeneID	3560
NCBI Accession	NP_000869.1
KEGG	hsa:3560
String	9606.ENSP00000216223
Molecular Weight	Calculated MW: 61 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 2 Receptor Beta (IL2RB)

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