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Interleukin 7 (IL7) Antibody
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Catalogue No: abx001389
Price:
US$203.00
(Size: 20 µl)
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IL7 Antibody is a Rabbit Polyclonal antibody against IL7. The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Research Articles on Interleukin 7 (IL7)
| Target | Interleukin 7 (IL7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 26-177 of human IL7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P13232 (UniProt, ExPASy) |
| UniProt Secondary AC | A0N0L3, Q5FBY5, Q5FBY9 |
| UniProt Entry Name | IL7_HUMAN |
| Gene Symbol | IL7 |
| GeneID | 3574 |
| NCBI Accession | NP_000871.1 |
| KEGG | hsa:3574 |
| String | 9606.ENSP00000263851 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |