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Interleukin Enhancer Binding Factor 3 (ILF3) Antibody
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Catalogue No: abx001940
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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ILF3 Antibody is a Rabbit Polyclonal antibody against ILF3. This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008].
Research Articles on Interleukin Enhancer Binding Factor 3 (ILF3)
| Target | Interleukin Enhancer Binding Factor 3 (ILF3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ILF3 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12906 (UniProt, ExPASy) |
| UniProt Entry Name | ILF3_HUMAN |
| Gene Symbol | ILF3 |
| GeneID | 3609 |
| NCBI Accession | NP_036350.2 |
| KEGG | hsa:3609 |
| String | 9606.ENSP00000404121 |
| Molecular Weight | Calculated MW: 74 kDa/75 kDa/76 kDa/82 kDa/95 kDa Observed MW: 95 kDa/120 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
