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Integrin-Linked Protein Kinase Phospho-Thr173 (ILK pT173) Antibody
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Catalogue No: abx032006
Price:
US$326.25
(Size: 80 µl)
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Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Research Articles on Integrin-Linked Protein Kinase Phospho-Thr173 (ILK pT173)
| Target | Integrin-Linked Protein Kinase Phospho-Thr173 (ILK pT173) |
| Clonality | Polyclonal |
| Target Modification | Thr173 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T173 of human ILK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13418 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z1I0, B7Z418, D3DQU0, P57043, Q68DZ3 |
| UniProt Entry Name | ILK_HUMAN |
| Gene Symbol | ILK |
| GeneID | 3611 |
| OMIM | 602366 |
| HGNC | 6040 |
| KEGG | hsa:3611 |
| Ensembl | ENSG00000166333 |
| String | 9606.ENSP00000379975 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | Calculated MW: 51.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Chicken ILK. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |