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Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) Antibody
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Catalogue No: abx033370
Price:
US$326.25
(Size: 80 µl)
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IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Research Articles on Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2)
| Target | Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 180-210 amino acids from the Central region of human IMPDH2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12268 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6LEF3 |
| UniProt Entry Name | IMDH2_HUMAN |
| KEGG | hsa:3615 |
| String | 9606.ENSP00000321584 |
| Molecular Weight | Calculated MW: 55.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Hamster and Zebrafish IMPDH2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |