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Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) Antibody
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Catalogue No: abx004091
Price:
US$348.00
(Size: 60 µl)
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IMPDH2 Antibody is a Rabbit Polyclonal antibody against IMPDH2. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Research Articles on Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2)
| Target | Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human IMPDH2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12268 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6LEF3 |
| UniProt Entry Name | IMDH2_HUMAN |
| Gene Symbol | IMPDH2 |
| GeneID | 3615 |
| NCBI Accession | NP_000875.2 |
| KEGG | hsa:3615 |
| String | 9606.ENSP00000321584 |
| Molecular Weight | Calculated MW: 55 kDa Observed MW: 56 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |