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Indoleamine 2,3-Dioxygenase 1 (INDO) Antibody
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Catalogue No: abx001358
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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INDO Antibody is a Rabbit Polyclonal antibody against INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Research Articles on Indoleamine 2,3-Dioxygenase 1 (INDO)
| Target | Indoleamine 2,3-Dioxygenase 1 (INDO) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human IDO1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14902 (UniProt, ExPASy) |
| UniProt Secondary AC | E5RGR8, F6M9T7, Q540B4 |
| Gene Symbol | IDO1 |
| GeneID | 3620 |
| NCBI Accession | NP_002155.1 |
| Molecular Weight | Calculated MW: 45 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
