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Inhibitor of Growth Protein 3 (ING3) Antibody
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Catalogue No: abx004471
Price:
US$203.00
(Size: 20 µl)
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ING3 Antibody is a Rabbit Polyclonal antibody against ING3. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Research Articles on Inhibitor of Growth Protein 3 (ING3)
| Target | Inhibitor of Growth Protein 3 (ING3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human ING3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NXR8 (UniProt, ExPASy) |
| UniProt Entry Name | ING3_HUMAN |
| Gene Symbol | ING3 |
| GeneID | 54556 |
| NCBI Accession | NP_938008.1 |
| String | 9606.ENSP00000320566 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |