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Inhibin Alpha (INHA) Antibody
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Catalogue No: abx010990
Price:
US$420.50
(Size: 100 µl)
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INHA (A-inhibin subunit precursor, inhibin alpha subunit), also called inhibin (alpha),which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
Research Articles on Inhibin Alpha (INHA)
| Target | Inhibin Alpha (INHA) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human INHA expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05111 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8H5 |
| UniProt Entry Name | INHA_HUMAN |
| Gene Symbol | INHA |
| GeneID | 3623 |
| OMIM | 147380 |
| HGNC | 6065 |
| KEGG | hsa:3623 |
| Ensembl | ENSG00000123999 |
| String | 9606.ENSP00000243786 |
| Molecular Weight | 40 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |