Inhibin Beta A (INHBA) Antibody

Inhibin Beta A (INHBA) Antibody is a Rabbit Polyclonal antibody against INHBA. The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Target	Inhibin Beta A (INHBA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-426 of human Inhibin beta A (INHBA).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08476 (UniProt, ExPASy)
UniProt Secondary AC	Q14599
UniProt Entry Name	INHBA_HUMAN
Gene Symbol	INHBA
GeneID	3624
NCBI Accession	NP_002183.1
KEGG	hsa:3624
String	9606.ENSP00000242208
Molecular Weight	Calculated MW: 47 kDa Observed MW: 47 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	0.627 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Inhibin Beta A (INHBA)

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