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NF-Kappa-B Essential Modulator (IKBKG) Antibody
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Catalogue No: abx010761
Price:
US$406.00
(Size: 100 µg)
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NF-Kappa-B Essential Modulator (IKBKG) Antibody is a Rabbit Polyclonal antibody for the detection of IKBKG. This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Research Articles on NF-Kappa-B Essential Modulator (IKBKG)
| Target | NF-Kappa-B Essential Modulator (IKBKG) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9Y6K9 (UniProt, ExPASy) |
| UniProt Secondary AC | Q7LBY6, Q7Z7F1 |
| UniProt Entry Name | NEMO_HUMAN |
| Gene Symbol | IKBKG |
| GeneID | 8517 |
| OMIM | 300248 |
| HGNC | 5961 |
| Ensembl | ENSG00000269335 |
| String | 9606.ENSP00000483825 |
| Molecular Weight | Observed MW: 40-55 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |