Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 (IF2B3) Antibody

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Catalogue No: abx240209
Price: US$406.00
(Size: 100 µg)
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WB analysis of A549 cell lysates, using IGF2BP3 antibody (1/1000 dilution).
Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 (IF2B3) Antibody

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Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 (IF2B3) Antibody is a Rabbit Polyclonal antibody for the detection of IGF2BP3.

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Target Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 (IF2B3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen insulin-like growth factor 2 mRNA binding protein 3
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC O00425 (UniProt, ExPASy)
UniProt Secondary AC A0A4Z5, Q63HM0, Q6MZZ2, Q86VB1
UniProt Entry Name IF2B3_HUMAN
KEGG hsa:10643
String 9606.ENSP00000258729
Molecular Weight Observed MW: 63 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 (IF2B3)
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