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Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) Antibody
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Catalogue No: abx033565
Price:
US$326.25
(Size: 80 µl)
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3) is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Research Articles on Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3)
| Target | Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17936 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2F5, D3DVM0, Q2V509, Q6P1M6, Q9UCL4 |
| UniProt Entry Name | IBP3_HUMAN |
| NCBI Accession | NP_000589.2 NP_001013416.1 |
| KEGG | hsa:3486 |
| String | 9606.ENSP00000370473 |
| Molecular Weight | Calculated MW: 31.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat IGFBP3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |