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Integrin Alpha-E / CD103 (ITGAE) Antibody
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Catalogue No: abx216265
Price:
US$406.00
(Size: 100 µg)
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Integrin Alpha-E / CD103 (ITGAE) Antibody is a Rabbit Polyclonal antibody for the detection of ITGAE. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Research Articles on Integrin Alpha-E / CD103 (ITGAE)
| Target | Integrin Alpha-E / CD103 (ITGAE) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ITGAE |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P38570 (UniProt, ExPASy) |
| UniProt Secondary AC | Q17RS6, Q9NZU9 |
| UniProt Entry Name | ITAE_HUMAN |
| Gene Symbol | ITGAE |
| GeneID | 3682 |
| OMIM | 604682 |
| HGNC | 6147 |
| KEGG | hsa:3682 |
| Ensembl | ENSG00000083457 |
| String | 9606.ENSP00000263087 |
| Molecular Weight | Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |