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Integrin Beta 2 (ITGB2) Antibody
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Catalogue No: abx216337
Price:
US$406.00
(Size: 100 µg)
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Integrin Beta 2 (ITGB2) Antibody is a Rabbit Polyclonal antibody for the detection of ITGB2. This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
Research Articles on Integrin Beta 2 (ITGB2)
| Target | Integrin Beta 2 (ITGB2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ITGB2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P05107 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KTS8, D3DSM1, Q16418, Q53HS5, Q9UD72 |
| UniProt Entry Name | ITB2_HUMAN |
| Gene Symbol | ITGB2 |
| GeneID | 3689 |
| OMIM | 116920 |
| HGNC | 6155 |
| KEGG | hsa:3689 |
| Ensembl | ENSG00000160255 |
| String | 9606.ENSP00000380948 |
| Molecular Weight | Observed MW: 85 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |