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Interferon Beta 1 (IFNB1) Antibody
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Catalogue No: abx216156
Price:
US$406.00
(Size: 100 µg)
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Interferon Beta 1 (IFNB1) Antibody is a Rabbit Polyclonal antibody for the detection of IFNB1. This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Research Articles on Interferon Beta 1 (IFNB1)
| Target | Interferon Beta 1 (IFNB1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Interferon beta |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P01574 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VWC9 |
| UniProt Entry Name | IFNB_HUMAN |
| Gene Symbol | IFNB1 |
| GeneID | 3456 |
| OMIM | 147640 |
| HGNC | 5434 |
| KEGG | hsa:3456 |
| Ensembl | ENSG00000171855 |
| String | 9606.ENSP00000369581 |
| Molecular Weight | Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |