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Interleukin 3 Receptor alpha (IL3RA) Antibody
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Catalogue No: abx015893
Price:
US$427.75
(Size: 100 µl)
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The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor.The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).The binding of this protein to IL3 depends on the beta subunit.The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.Alternatively spliced transcript variants encoding distinct isoforms have been found.; ; ; ;.
Research Articles on Interleukin 3 Receptor alpha (IL3RA)
| Target | Interleukin 3 Receptor alpha (IL3RA) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P26951 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3F3, B9VI81, Q5HYQ7, Q5HYQ8, Q9UEH7 |
| UniProt Entry Name | IL3RA_HUMAN |
| Gene Symbol | IL3RA |
| GeneID | 3563 |
| OMIM | 308385 |
| HGNC | 6012 |
| KEGG | hsa:3563 |
| Ensembl | ENSG00000185291 |
| String | 9606.ENSP00000327890 |
| Molecular Weight | 43.3 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |