Interleukin 3 Receptor alpha (IL3RA) Antibody

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor.The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).The binding of this protein to IL3 depends on the beta subunit.The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.Alternatively spliced transcript variants encoding distinct isoforms have been found.; ; ; ;.

Target	Interleukin 3 Receptor alpha (IL3RA)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P26951 (UniProt, ExPASy)
UniProt Secondary AC	A8K3F3, B9VI81, Q5HYQ7, Q5HYQ8, Q9UEH7
UniProt Entry Name	IL3RA_HUMAN
Gene Symbol	IL3RA
GeneID	3563
OMIM	308385
HGNC	6012
KEGG	hsa:3563
Ensembl	ENSG00000185291
String	9606.ENSP00000327890
Molecular Weight	43.3 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 3 Receptor alpha (IL3RA)

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