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Insulin Promoter Factor 1 (IPF) Antibody
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Catalogue No: abx033653
Price:
US$326.25
(Size: 80 µl)
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IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Research Articles on Insulin Promoter Factor 1 (IPF)
| Target | Insulin Promoter Factor 1 (IPF) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 43-72 amino acids from human IPF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52945 (UniProt, ExPASy) |
| UniProt Secondary AC | O60594, Q5VYW2 |
| UniProt Entry Name | PDX1_HUMAN |
| NCBI Accession | NP_000200.1 |
| KEGG | hsa:3651 |
| String | 9606.ENSP00000370421 |
| Molecular Weight | Calculated MW: 30.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat PDX1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |